1.1.1.262: 4-hydroxythreonine-4-phosphate dehydrogenase
This is an abbreviated version!
For detailed information about 4-hydroxythreonine-4-phosphate dehydrogenase, go to the full flat file.
Reaction
Synonyms
4-(phosphohydroxy)-L-threonine dehydrogenase, L-threonine 4-phosphate dehydrogenase, NAD-dependent threonine 4-phosphate dehydrogenase, PdxA
ECTree
Advanced search results
Reaction
Reaction on EC 1.1.1.262 - 4-hydroxythreonine-4-phosphate dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
3-amino-1-hydroxyacetone 1-phosphate,i.e. AHAB, is the primary product of the reaction, no formation of 2-amino-3-oxo-4-phosphonooxybutyrate as intermediate is detected, identification by electrospray ionization mass spectrometry
-
4-phosphooxy-L-threonine + NAD+ = 3-amino-2-oxopropyl phosphate + CO2 + NADH + H+
Asp247 and Asp267 are involved in formation and maintaining of the integrity of the active site