1.1.1.236: tropinone reductase II

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For detailed information about tropinone reductase II, go to the full flat file.

Word Map on EC 1.1.1.236

1.1.1.236

tropane

reductases

stramonium

datura

scopolamine

calystegines

solanaceae

hyoscyamine

hyoscyamus

tuberosum

solanum

tuber

solanaceous

alkaloid-producing

n-methylputrescine

3-quinuclidinone

enemies

stereoisomeric

herbivores

n-methyltransferase

nortropane

nonmetal

Reaction

Synonyms

DnTR2, More, pseudotropine forming tropinone reductase, pseudotropine reductase II, pseudotropine-forming tropinone reductase, pseudotropinone forming tropinone reductase, TR-II, TR2, TRII, tropinone (psi-tropine-forming) reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-II

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.236 tropinone reductase II

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Results	in table
1	Activating Compound
24	AA Sequence
1	CAS Registry Number
24	Cloned(Commentary)
34	Cofactor
4	Crystallization (Commentary)
1	Expression
11	General Information
5	General Stability
2	Inhibitors
1	kcat/KM [mM/s]
82	KM Value [mM]
21	Molecular Weight [Da]
54	Natural Substrates/ Products (Substrates)
72	Organism
3	Pathway
11	PDB ID
17	pH Optimum
3	pH Range
3	pH Stability
2	pI Value
2	Protein Variants
21	Purification (Commentary)
1	Reaction
3	Reaction Type
71	Reference
85	Source Tissue
8	Specific Activity [micromol/min/mg]
3	Storage Stability
132	Substrates and Products (Substrate)
24	Subunits
39	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
5	Turnover Number [1/s]

Purification

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Purification on EC 1.1.1.236 - tropinone reductase II

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5 entries

HiTrap chelating HP Sepharose column chromatography

Solanum tuberosum

670636

recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography

Solanum dulcamara

689953

recombinant His6-tagged wild-type and mutant enzymes from Escherichia coli strain BL21(DE3) by nickel affinity chromatography

Dendrobium nobile

H9BQR9

740901

recombinant StTRII L1

Solanum tuberosum

348033