1.1.1.235: 8-oxocoformycin reductase
This is an abbreviated version!
For detailed information about 8-oxocoformycin reductase, go to the full flat file.
Reaction
Synonyms
8-ketodCF reductase, 8-ketodeoxycoformycin reductase
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.235 - 8-oxocoformycin reductase
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REACTION DIAGRAM
coformycin + NADP+
-
stereospecifically reduces the 8-keto group of the ketonucleoside substrate to a hydroxyl group with the R configuration at C-8
-
r
8-ketocoformycin + NADPH
coformycin + NADP+
-
production of the antibiotic coformycin
-
r
2'-deoxycoformycin + NADP+
-
stereospecifically reduces the 8-keto group of the ketonucleoside substrate to a hydroxyl group with the R configuration at C-8
-
r
8-ketodeoxycoformycin + NADPH
2'-deoxycoformycin + NADP+
-
production of the antibiotic 2'-deoxycoformycin
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r