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1.1.1.23: histidinol dehydrogenase

This is an abbreviated version!
For detailed information about histidinol dehydrogenase, go to the full flat file.

Reaction

L-histidinol
+ 2 NAD+ +
H2O
=
L-histidine
+ 2 NADH + 2 H+

Synonyms

11412251, BN980_GECA03s06082g, BsHDH, GcHDH, HDH, HIS4 protein, HisD, histidinol dehydrogenase, HLDase, L-histidinol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.23 histidinol dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.23 - histidinol dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-histidinal + NAD+ + H2O
L-histidine + NADH + H+
show the reaction diagram
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 2 H+
show the reaction diagram
L-histidinol + 2 NAD+ + H2O
L-histidine + 2 NADH + 3 H+
show the reaction diagram
L-histidinol + NAD+
L-histidinal + NADH + H+
show the reaction diagram
-
enzyme is responsible for catalysis of the terminal step in L-histidine biosynthesis, being performed in 2 sequential reactions via the intermediate L-histidinal
-
-
ir