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1.1.1.216: farnesol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about farnesol dehydrogenase (NADP+), go to the full flat file.

Reaction

(2E,6E)-farnesol
+
NADP+
=
(2E,6E)-farnesal
+
NADPH
+
H+

Synonyms

dehydrogenase, farnesol (nicotinamide adenine dinucleotide phosphate), More, NAD(P)+-dependent farnesol dehydrogenase, NADP+-dependent farnesol dehydrogenase 1, NADP-farnesol dehydrogenase, SDR-1

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.216 farnesol dehydrogenase (NADP+)

pH Range

pH Range on EC 1.1.1.216 - farnesol dehydrogenase (NADP+)

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6 - 9
-
reduction of trans,trans-farnesal: 60% of maximal activity at pH 6.5 and at pH 8
7 - 10.5
-
oxidation of trans,trans-farnesol: 10% of maximal activity at pH 7.0, 30% of maximal activity at pH 10.2
7.5 - 11
-
activity range, profile overview. At below pH 8.5 or above pH 10.0, the enzyme activity declines sharply