1.1.1.215: gluconate 2-dehydrogenase

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For detailed information about gluconate 2-dehydrogenase, go to the full flat file.

Reaction

Synonyms

2-HDH, 2-keto-D-gluconate reductase, 2-keto-D-gluconate-yielding D-gluconate dehydrogenase, 2-keto-L-gulonate reductase, 2-ketoaldonate reductase, 2-ketogluconate dehydrogenase, 2-ketogluconate reductase, 2KGA reductase, 2KGR, 2KR, FAD-GADH, GA2DH, GAD, GADH, gluconate dehydrogenase, gluconate-2-dehydrogenase, gluconate-2-DH, GluD, Gox0417, GOX1230, HDH, L-2-hydroxyacid dehydrogenase, NADP-gluconate 2-dehydrogenase, NADPH requiring 2-keto-L-gulonate reductase, reductase, 2-ketogluconate

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.215 gluconate 2-dehydrogenase

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Results	in table
1	Activating Compound
575	AA Sequence
6	Application
1	CAS Registry Number
12	Cloned(Commentary)
39	Cofactor
6	Crystallization (Commentary)
2	Expression
16	General Information
6	General Stability
19	Inhibitors
5	kcat/KM [mM/s]
27	KM Value [mM]
22	Localization
8	Metals/Ions
20	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
10	Organic Solvent Stability
44	Organism
6	Pathway
18	pH Optimum
5	pH Range
6	pH Stability
2	pI Value
11	Protein Variants
10	Purification (Commentary)
1	Reaction
3	Reaction Type
37	Reference
2	Source Tissue
8	Specific Activity [micromol/min/mg]
8	Storage Stability
104	Substrates and Products (Substrate)
15	Subunits
57	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
2	Temperature Range [°C]
9	Temperature Stability [°C]
3	Turnover Number [1/s]

Turnover Number

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

48.2

2-oxo-D-gluconate

Gluconobacter oxydans

Q5FTU6

pH 7.0, 25°C

721369

21.4

2-oxo-L-gulonate

Aspergillus niger

A0A1D8RK43

pH 7, temperature not specified in the publication

761153

1.1

L-Idonate

Aspergillus niger

A0A1D8RK43

pH 8, temperature not specified in the publication

761153