1.1.1.21: aldose reductase

This is an abbreviated version!
For detailed information about aldose reductase, go to the full flat file.

Word Map on EC 1.1.1.21

1.1.1.21

lens

nerve

neuropathy

sorbinil

cataract

mellitus

retinopathy

hyperglycemia

glycation

streptozotocin

galactose

sciatic

fructose

retinal

endothelial

streptozotocin-induced

myo-inositol

erythrocyte

reductases

nadph-dependent

streptozotocin-diabetic

microvascular

galactosemic

galactitol

hypertonic

diabetes-induced

stz-induced

opacity

antidiabetic

glucose-induced

osmolytes

pericytes

nondiabetic

cataractogenesis

galactose-induced

microangiopathy

endoneurial

xylitol

sural

hne

hyperglycemia-induced

polyneuropathy

lenticular

glycaemic

mesangial

synthesis

opacification

stz-diabetic

alr

akr1c3

microaneurysms

nutrition

medicine

drug development

diagnostics

biotechnology

Reaction

Synonyms

17betaHSD5, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, AdhA, AKR1B, AKR1B1, AKR1B10, AKR1B13, AKR1B14, AKR1B3, AKR1C3, AKR4C7, aldehyde reductase, alditol/NADP+ oxidoreductase, alditol: NADP+ 1-oxidoreductase, alditol:NAD(P)+1oxidoreductase, alditol:NADP 1-oxidoreductase, alditol:NADP oxidoreductase, aldo-keto reductase, aldo-keto reductase family 1 member B1, aldo-keto reductase family 1 member B7, aldoketo reductase 1C3, aldose reductase, aldose reductase 2, aldose reductase-like, aldose reductase-like protein, aldose xylose reductase, ALDRXV4, ALR, ALR1, ALR2, AR, ARI, BAR, EC 1.1.1.139, Fibroblast growth factor regulated protein, FR-1 protein, GRE3, HAR, HRAR, isobutyraldehyde reductase, More, MVDP, NADPH dependent xylose reductase, NADPH-aldopentose reductase, NADPH-aldose reductase, polyol dehydrogenase (NADP2), RLAR, small intestine reductase, TPN-polyol dehydrogenase, VAS deferens androgen-dependent protein, YqhD

Results	in table
40	Activating Compound
317	AA Sequence
30	Application
1	CAS Registry Number
42	Cloned(Commentary)
145	Cofactor
31	Crystallization (Commentary)
5524	Disease/ Diagnostics
9	Expression
72	General Information
12	General Stability
719	IC50 Value
1440	Inhibitors
12	kcat/KM [mM/s]
64	Ki Value [mM]
286	KM Value [mM]
6	Localization
6	Metals/Ions
52	Molecular Weight [Da]
100	Natural Substrates/ Products (Substrates)
820	Organism
15	Pathway
196	PDB ID
65	pH Optimum
7	pH Range
6	pH Stability
2	pI Value
5	Posttranslational Modification
51	Protein Variants
55	Purification (Commentary)
10	Reaction
2	Reaction Type
248	Reference
238	Source Tissue
35	Specific Activity [micromol/min/mg]
7	Storage Stability
583	Substrates and Products (Substrate)
41	Subunits
261	Synonyms
1	Systematic Name
43	Temperature Optimum [°C]
2	Temperature Range [°C]
5	Temperature Stability [°C]
134	Turnover Number [1/s]

1.1.1.21: aldose reductase

Reaction

Synonyms

ECTree

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Molecular Weight

Molecular Weight on EC 1.1.1.21 - aldose reductase