1.1.1.208: (+)-neomenthol dehydrogenase
This is an abbreviated version!
For detailed information about (+)-neomenthol dehydrogenase, go to the full flat file.
Reaction
Synonyms
(-)-menthone:(+)-neomenthol reductase, (-)-menthone:(3S)-neomenthol reductase, dehydrogenase, neomenthol, menthone:(+)-(3S)-neomenthol reductase, menthone:(+)-neomenthol reductase, MNMR, MNR, monoterpenoid dehydrogenase, More, Red 1
ECTree
1.1.1.208 (+)-neomenthol dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.1.1.208 - (+)-neomenthol dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(+)-neomenthol + NADP+
(-)-menthone + NADPH + H+
reaction proceeds via (-)-menthone
-
-
r
(-)-menthone + NADPH + H+
(+)-neomenthol + NADP+
-
main product, plus some (-)-menthol
-
r
(-)-menthone + NADPH + H+
(+)-neomenthol + NADP+
-
-
-
r
(-)-menthone + NADPH + H+
(+)-neomenthol + NADP+
-
-
-
r
(-)-menthone + NADPH + H+
(+)-neomenthol + NADP+
menthone reduction is the physiological reaction of enzyme MNMR
-
-
r
(-)-menthone + NADPH + H+
(3S)-neomenthol + NADP+
in vitro antimicrobial activities of menthone, neomenthol and menthol, overview
-
-
r
(-)-menthone + NADPH + H+
(3S)-neomenthol + NADP+
CaMNR1 converts (-)-menthone to 93% (3S)-neomenthol and 7% (3R)-menthol at pH 7.5, and to 72% (3S)-neomenthol and 28% (3R)-menthol at pH 9.0 with NADPH as a cofactor
-
-
r
(-)-menthone + NADPH + H+
(3S)-neomenthol + NADP+
-
low activity in the reverse reaction
(3S)-neomenthol is the main product, product determination by gas chromatography, overview
-
r
additional information
?
-
the menthone reductase gene CaMNR1 positively regulates plant defenses against a broad spectrum of pathogens, overview
-
-
?
additional information
?
-
no substrates for reduction: carvone and isopiperitenone. No substrates in dehydrogenase reaction: (+)-borneol, (-)-borneol, (+)-menthol and (-)-neomenthol
-
-
?
additional information
?
-
CaMNR1 gene plays a role in regulating the resistance of pepper plants at the mRNA and protein levels, the menthone reductase gene CaMNR1 positively regulates plant defenses against a broad spectrum of pathogens, overview
-
-
?
additional information
?
-
-
primary monoterpene biosynthesis pathway, overview
-
-
?
additional information
?
-
enzyme MNMR has a preference for menthone over isomenthone
-
-
?
