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1.1.1.206: tropinone reductase I

This is an abbreviated version!
For detailed information about tropinone reductase I, go to the full flat file.

Word Map on EC 1.1.1.206

Reaction

Tropine
+
NADP+
=
tropinone
+
NADPH
+
H+

Synonyms

BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, EC 1.1.1.293, More, TR-I, TR1, TRI, Tri2, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, tropinone reductase-I 2, WcTR-I, WsTR-I, WsTR-I protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.206 tropinone reductase I

Turnover Number

Turnover Number on EC 1.1.1.206 - tropinone reductase I

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
8.97
3-methylcyclohexanone
recombinant enzyme, pH 6.7, 30°C
0.54
3-quinuclidinone
pH 9.6, 22°C, recombinant His-tagged enzyme
4.67
4-methylcyclohexanone
pH 6.4, 22°C, recombinant His-tagged enzyme
9.23
N-methylpiperidine
recombinant enzyme, pH 6.7, 30°C
0.54 - 2.94
NADP+
6.76 - 33.34
NADPH
1.67 - 5.69
Tropine
0.98 - 42.26
tropinone