1.1.1.200: aldose-6-phosphate reductase (NADPH)
This is an abbreviated version!
For detailed information about aldose-6-phosphate reductase (NADPH), go to the full flat file.
Word Map on EC 1.1.1.200
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1.1.1.200
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sorbitol
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apple
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domestica
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malus
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starch
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rosaceae
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peach
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adp-glucose
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borkh
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2.4.1.14
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hexokinase
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sink
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invertase
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greensleeves
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fructokinase
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pyrophosphorylase
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prunus
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2.7.7.27
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gala
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sugar-phosphates
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aldo-keto
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sink-source
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glucitol
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persica
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mixed-type
- 1.1.1.200
- sorbitol
- apple
- domestica
- malus
- starch
- rosaceae
- peach
- adp-glucose
-
borkh
-
2.4.1.14
- hexokinase
-
sink
- invertase
-
greensleeves
- fructokinase
-
pyrophosphorylase
-
prunus
-
2.7.7.27
-
gala
-
sugar-phosphates
-
aldo-keto
-
sink-source
- glucitol
- persica
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mixed-type
Reaction
Synonyms
A6PR, A6PR1, A6PR2, A6PRase, Ald6PRase, alditol 6-phosphate:NADP 1-oxidoreductase, aldose-6-P reductase, aldose-6-phosphate reductase, aldose-6-phosphate reductase [NADPH], NADP-S6PDH, NADPH-dependent aldose 6-phosphate reductase, reductase, aldose 6-phosphate, S6PDH, sorbitol-6-phosphate dehydrogenase
ECTree
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Inhibitors
Inhibitors on EC 1.1.1.200 - aldose-6-phosphate reductase (NADPH)
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cysteine
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47% inhibition of oxidation and 11% inhibition of reduction at 10 mM
Diamide
enzymatic activity decreases to approximately 7% at 500 mM diamide
H2O2
H2O2 oxidation causes enzyme inactivation in a time- and concentration-dependent manner
iodoacetate
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42% inhibition of oxidation and 19% inhibition of reduction at 10 mM
Na2EDTA
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35% inhibition of oxidation and 11% inhibition of reduction at 10 mM
ZnSO4
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complete inhibition of oxidation and 80% inhibition of reduction at 1.25 mM
no significant differences in activity when ATP, ADP, AMP, ADP-glucose, UTP, UDP-glucose, inorganic phosphate or diphosphate (5 mM each), 10% (v/v) glycerol, 500 mM glucitol or 20% (w/v) sucrose are added to the enzyme assay mixture
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additional information
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no significant differences in activity when ATP, ADP, AMP, ADP-glucose, UTP, UDP-glucose, inorganic phosphate or diphosphate (5 mM each), 10% (v/v) glycerol, 500 mM glucitol or 20% (w/v) sucrose are added to the enzyme assay mixture
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additional information
no inhibition by D-trehalose 6-phosphate, D-fructose 2,6-bisphosphate, D-xylitol, D-glucose and D-fructose. Not affected by 5 mM GSSG
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additional information
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no inhibition by D-trehalose 6-phosphate, D-fructose 2,6-bisphosphate, D-xylitol, D-glucose and D-fructose. Not affected by 5 mM GSSG
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