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1.1.1.2: alcohol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about alcohol dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.2

Reaction

a primary alcohol
+
NADP+
=
an aldehyde
+
NADPH
+
H+

Synonyms

2° Adh, 3-DG-reducing enzyme, A3L14_07690, AAur_2040, ADH, ADH-1, ADH-2, ADH-I, ADH-II, ADH2, Adh319, ADH4, Adh6, AdhA, AdhB, AdhD, AKR1A1, AKR1A4, alcohol dehydrogenase C, alcohol dehydrogenase D, alcohol dehydrogenase [NADP(+)], Alcohol dehydrogenase [NADP+], aldehyde reductase, aldehyde reductase (NADPH2), aldehyde/ketone reductase, aldo-keto reductase, Aldo-keto reductase family 1 member A1, aldose reductase, ALDR, alipathic aldehyde reductase, ALR, ALR 1, ALR1, BdhA, bovine brain aldehyde reductase, CbADH, D-glucuronate reductase, daunorubicin reductase, DRD, EhADH1, FeADH, Gre2p, hexogenate dehydrogenase, high-Km aldehyde reductase, HvADH2, iron-containing alcohol dehydrogenase, KpADH, L-hexonate dehydrogenase, LB-RADH, LBADH, liver alcohol dehydrogenase, low-Km aldehyde reductase, mevaldate reductase, Mpd1, NADP(H)-dependent alcohol dehydrogenase, NADP+-dependent alcohol dehydrogenase, NADP-alcohol dehydrogenase, NADP-aldehyde reductase, NADP-dependent aldehyde reductase, NADP-linked aryl alcohol dehydrogenase, NADPH-aldehyde reductase, NADPH-cytochrome c reductase, NADPH-dependent ADH, NADPH-dependent aldehyde reductase, NADPH-dependent FALDR, NADPH-dependent fatty aldehyde reductase, NADPH-linked aldehyde reductase, nonspecific succinic semialdehyde reductase, Octopine dehydrogenase, putative iron alcohol dehydrogenase, PyAeADHII, rabbit kidney aldehyde-ketone reductase, RADH, ScADHVI, short-chain ADH, short-chain alcohol dehydrogenase, short-chain dehydrogenase/reductase, TBADH, TbADH1, Teth39_1597, Teth514_0564, TPN-L-hexonate dehydrogenase, TPNH-linked aldehyde reductase, TPNH-specific aldehyde reductase, triphosphopyridine nucleotide-linked aldehyde reductase, TsAdh319, Y63 protein, yeast alcohol dehydrogenase, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.2 alcohol dehydrogenase (NADP+)

KCat KM Value

KCat KM Value on EC 1.1.1.2 - alcohol dehydrogenase (NADP+)

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
49
(2R,3R)-2,3-butanediol
cosubstrate: NADP+, pH 7.5, 80°C
2.08
(2S,3S)-2,3-butanediol
cosubstrate: NADP+, pH 7.5, 80°C
0.0069 - 0.639
(R)-1-phenyl-2-propanol
0.551 - 45.3
(S)-1-phenyl-2-propanol
0.033
1,4-Butanediol
-
pH 9.5, 30°C, mutant V84I/Y127M
230
1,5-pentanediol
pH 7.0. 30°C
2192
2-butanol
cosubstrate: NADP+, pH 7.5, 80°C
613
2-butanone
cosubstrate: NADPH, pH 7.5, 80°C
0.0000032 - 0.00025
2-hydroxytetrahydrofuran
-
0.3
2-Pentanol
pH 10.0, 70°C
300
2-phenylacetaldehyde
-
pH 8.0, 80°C
2.1
2-phenylethanol
-
pH 8.0, 80°C
716
3,4-dihydro-1(2H)-naphthalenone
-
95°C, pH 7.5
760
3-methyl-1,5-pentanediol
pH 7.0. 30°C
0.0028 - 76.4
acetaldehyde
444
acetoin
cosubstrate: NADPH, pH 7.5, 80°C
160
butan-1-ol
pH 7.0. 30°C
3
Butanal
pH 7.0, temperature not specified in the publication
962
diacetyl
cosubstrate: NADPH, pH 7.5, 80°C
0.65 - 6
ethanol
49
meso-2,3-butanediol
cosubstrate: NADP+, pH 7.5, 80°C
1160 - 1420
methyl 4-bromo-3-oxobutanoate
18.5
methylglyoxal
-
80°C, pH not specified in the publication
0.12 - 26.7
NAD+
0.13 - 5724
NADH
119.9 - 3333
NADP+
0.54 - 14360
NADPH
67.2
octan-1-ol
pH 8, 60°C
450.8
octanal
pH 8, 60°C
123.1
pentanal
pH 7.0, temperature not specified in the publication
114
phenylacetaldehyde
-
80°C, pH not specified in the publication
4.2
Pyruvaldehyde
pH 7.0, 70°C