1.1.1.2: alcohol dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

2� Adh, 3-DG-reducing enzyme, A3L14_07690, AAur_2040, ADH, ADH-1, ADH-2, ADH-I, ADH-II, ADH2, Adh319, ADH4, Adh6, AdhA, AdhB, AdhD, AKR1A1, AKR1A4, alcohol dehydrogenase C, alcohol dehydrogenase D, alcohol dehydrogenase [NADP(+)], Alcohol dehydrogenase [NADP+], aldehyde reductase, aldehyde reductase (NADPH2), aldehyde/ketone reductase, aldo-keto reductase, Aldo-keto reductase family 1 member A1, aldose reductase, ALDR, alipathic aldehyde reductase, ALR, ALR 1, ALR1, BdhA, bovine brain aldehyde reductase, CbADH, D-glucuronate reductase, daunorubicin reductase, DRD, EhADH1, FeADH, Gre2p, hexogenate dehydrogenase, high-Km aldehyde reductase, HvADH2, iron-containing alcohol dehydrogenase, KpADH, L-hexonate dehydrogenase, LB-RADH, LBADH, liver alcohol dehydrogenase, low-Km aldehyde reductase, mevaldate reductase, Mpd1, NADP(H)-dependent alcohol dehydrogenase, NADP+-dependent alcohol dehydrogenase, NADP-alcohol dehydrogenase, NADP-aldehyde reductase, NADP-dependent aldehyde reductase, NADP-linked aryl alcohol dehydrogenase, NADPH-aldehyde reductase, NADPH-cytochrome c reductase, NADPH-dependent ADH, NADPH-dependent aldehyde reductase, NADPH-dependent FALDR, NADPH-dependent fatty aldehyde reductase, NADPH-linked aldehyde reductase, nonspecific succinic semialdehyde reductase, Octopine dehydrogenase, putative iron alcohol dehydrogenase, PyAeADHII, rabbit kidney aldehyde-ketone reductase, RADH, ScADHVI, short-chain ADH, short-chain alcohol dehydrogenase, short-chain dehydrogenase/reductase, TBADH, TbADH1, Teth39_1597, Teth514_0564, TPN-L-hexonate dehydrogenase, TPNH-linked aldehyde reductase, TPNH-specific aldehyde reductase, triphosphopyridine nucleotide-linked aldehyde reductase, TsAdh319, Y63 protein, yeast alcohol dehydrogenase, YqhD

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.2 alcohol dehydrogenase (NADP+)

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Results	in table
11	Activating Compound
3079	AA Sequence
50	Application
1	CAS Registry Number
41	Cloned(Commentary)
97	Cofactor
25	Crystallization (Commentary)
1016	Disease/ Diagnostics
2	Expression
12	General Information
9	General Stability
33	IC50 Value
349	Inhibitors
70	kcat/KM [mM/s]
2	Ki Value [mM]
666	KM Value [mM]
36	Localization
29	Metals/Ions
171	Molecular Weight [Da]
234	Natural Substrates/ Products (Substrates)
7	Organic Solvent Stability
378	Organism
4	Oxidation Stability
18	Pathway
108	PDB ID
79	pH Optimum
12	pH Range
4	pH Stability
5	pI Value
63	Protein Variants
83	Purification (Commentary)
3	Reaction
5	Reaction Type
311	Reference
370	Source Tissue
149	Specific Activity [micromol/min/mg]
28	Storage Stability
1439	Substrates and Products (Substrate)
127	Subunits
167	Synonyms
1	Systematic Name
38	Temperature Optimum [°C]
5	Temperature Range [°C]
51	Temperature Stability [°C]
146	Turnover Number [1/s]

Expression

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Expression on EC 1.1.1.2 - alcohol dehydrogenase (NADP+)

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

transcription levels of isoform ADH4 display more than 100fold increase in response to furfural and 150fold increase in response to hydroxymethylfurfural, respectively

2 entries

transcription levels of isoform ADH4 display more than 100fold increase in response to furfural and 150fold increase in response to hydroxymethylfurfural, respectively

Scheffersomyces stipitis

A3GHL4, A3GHR6

737531

transcription levels of isoform ADH4 display more than 100fold increase in response to furfural and 150fold increase in response to hydroxymethylfurfural, respectively

Scheffersomyces stipitis ATCC 58785

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