1.1.1.198: (+)-borneol dehydrogenase
This is an abbreviated version!
For detailed information about (+)-borneol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.198
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1.1.1.198
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monoterpenes
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+-borneol
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refolded
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terpenoids
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+-camphor
-
synthesis
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isozyme
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taiwan
- 1.1.1.198
- monoterpenes
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+-borneol
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refolded
-
terpenoids
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+-camphor
- synthesis
- isozyme
-
taiwan
Reaction
Synonyms
AaBDH, ADH2, BDH, BDH1, BDH2, BDH3, bicyclic monoterpenol dehydrogenase, borneol dehydrogenase, borneol-type dehydrogenase 1, EC 1.1.1.182, TCK1_3449, THL1_4180
ECTree
1.1.1.198 (+)-borneol dehydrogenaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.1.1.198 - (+)-borneol dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(+)-borneol + (-)-isoborneol + NAD+
(+)-camphor + (-)-isoborneol + NADH + H+
-
the reaction is catalyzed by isoform BDH1
-
-
?
(+)-dihydrocarveol + NAD+
(-)-dihydrocarvone + NADH
-
poor substrate
-
?
(+)-endo-fenchol + NAD+
1,3,3-trimethyl-bicyclo[2.2.1]heptan-2-one + NADH
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26% of the activity compared to (+)-borneol
-
?
(+)-isoborneol + NAD+
(+)-isocamphor + NADH
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nearly the same activity compared to (+)-borneol
-
?
(-)-endo-fenchol + NAD+
1,3,3-trimethyl-bicyclo[2.2.1]heptan-2-one + NADH
-
poor substrate
-
?
(-)-isoborneol + NAD+
(-)-isocamphor + NADH
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30% of the activity compared to (+)-borneol
-
?
(-)-neothujol + NAD+
(-)-neothujone + NADH
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65% of the activity compared to (+)-borneol
-
?
(-)-thujol + NAD+
(-)-thujone + NADH
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2fold higher activity than for (+)-borneol
-
?
(1R)-(+)-camphor + (1S)-(-)-camphor + NADH + H+
(+)-borneol + (1S)-(-)-camphor + NAD+
Pseudomonas sp. ATCC 17453
-
-
-
-
?
(1R)-menthol + NAD+
(1R)-trans-p-menthan-3-one + NADH
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poor substrate
-
?
(+)-borneol + NAD+
(+)-camphor + NADH
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B-site stereospecific, partially reversible
-
r
(+)-borneol + NAD+
(+)-camphor + NADH + H+
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camphor is the only product
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ir
(+)-borneol + NAD+
(+)-camphor + NADH + H+
-
(+)-borneol is the preferred substrate
-
-
?
(+)-borneol + NAD+
(+)-camphor + NADH + H+
Pseudomonas monteilii TCU-CK1
-
(+)-borneol is the preferred substrate
-
-
?
(+)-borneol + NAD+
(+)-camphor + NADH + H+
stereospecific reaction
-
-
?
(+)-borneol + NAD+
(+)-camphor + NADH + H+
the enzyme prefers to degrade (+)-borneol, rather than (-)-borneol
-
-
?
(+)-borneol + NAD+
(+)-camphor + NADH + H+
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the reaction is catalyzed by isoform BDH2
-
-
?
(+/-)-isoborneol + NAD+
(-)-camphor + NADH + H+
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the reaction is catalyzed by isoform BDH2
-
-
?
(-)-borneol + NAD+
(-)-camphor + NADH + H+
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36% of the activity compared to (+)-borneol
-
?
(-)-borneol + NAD+
(-)-camphor + NADH + H+
-
the reaction is catalyzed by isoform BDH2
-
-
?
additional information
?
-
no substrates: citronellol, lavandulol, myrtenol, and (S)-(-)-perillyl alcohol, artemisinic alcohol, farnesol, khusinol, and santalol, secoisolariciresinol, larixol, phytol, retinol, benzyl alcohol, cinnamyl alcohol, 2-cyclohexen-1-ol, and 3-methyl-2-buten-1-ol
-
-
?
additional information
?
-
substrate specificity, overview. No activity with other monoterpene alcohol, several kinds of monoterpene alcohols including (-)-artemisia alcohol, cis-carveol, trans-carveol, and trans-pinocarveol. The enzyme is specific for (+)-borneol
-
-
?
additional information
?
-
no substrate: 1,8-cineole, citronellol, linalool, lavandulol, nerol, geraniol, perillyl alcohol, and farnesol. The reverse reduction assay in which camphor is used as a substrate and NADH as a cofactor, does not produce detectable amounts of borneol or other products
-
-
?
additional information
?
-
-
no substrate: 1,8-cineole, citronellol, linalool, lavandulol, nerol, geraniol, perillyl alcohol, and farnesol. The reverse reduction assay in which camphor is used as a substrate and NADH as a cofactor, does not produce detectable amounts of borneol or other products
-
-
?
additional information
?
-
-
(-)-borneol is an additional substrate, reaction of EC 1.1.1.227. (+)-Borneol is the preferred substrate
-
-
-
additional information
?
-
-
the recombinant enzyme does not use isopropanol, cyclohexanol, cyclopentanol, or(+/-)-2-butanol as alternative substrates, and NADP+ as a cofactor
-
-
-
additional information
?
-
Pseudomonas monteilii TCU-CK1
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(-)-borneol is an additional substrate, reaction of EC 1.1.1.227. (+)-Borneol is the preferred substrate
-
-
-
additional information
?
-
Pseudomonas monteilii TCU-CK1
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the recombinant enzyme does not use isopropanol, cyclohexanol, cyclopentanol, or(+/-)-2-butanol as alternative substrates, and NADP+ as a cofactor
-
-
-
additional information
?
-
-
enzyme also catalyzes the reaction of (-)-borneol and (-)-camphor, reaction of EC 1.1.1.227. No substrates: isopropanol, cyclopentanol, cyclohexanol, 1,2-butandiol, 2-butanol, L-carveol, and DL-menthol
-
-
-
additional information
?
-
-
enzyme also catalyzes the reaction of (-)-borneol and (-)-camphor, reaction of EC 1.1.1.227. No substrates: isopropanol, cyclopentanol, cyclohexanol, 1,2-butandiol, 2-butanol, L-carveol, and DL-menthol
-
-
-
additional information
?
-
GC-MS analysis of borneol degradation metabolites
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-
?
additional information
?
-
-
GC-MS analysis of borneol degradation metabolites
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-
?
additional information
?
-
the enzyme is also active with (-)-borneol, reaction of EC 1.1.1.227
-
-
?
additional information
?
-
-
the enzyme is also active with (-)-borneol, reaction of EC 1.1.1.227
-
-
?
additional information
?
-
Pseudomonas sp. ATCC 17453
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isopropanol, cyclopentanol, cyclohexanol, 1,2-butandiol, (+/-)-2-butanol, L-carveol, and DL-menthol are not accepted as substrates
-
-
-
additional information
?
-
-
enzyme additionally catalyzes the reaction with (-)-borneol, reaction of EC 1.1.1.227. (+)-Borneol is the preferred substrate
-
-
-
additional information
?
-
enzyme additionally catalyzes the reaction with (-)-borneol, reaction of EC 1.1.1.227. (+)-Borneol is the preferred substrate
-
-
-
additional information
?
-
-
isoforms BDH1 and BDH2 also accept monocyclic and linear substrates, clearly favoring secondary alcohols over primary alcohols. No substrate: menthol
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