1.1.1.19: glucuronate reductase

This is an abbreviated version!
For detailed information about glucuronate reductase, go to the full flat file.

Word Map on EC 1.1.1.19

1.1.1.19

aldo-keto

aldose

sorbinil

akr1b1s

o-quinones

alrestatin

1.1.1.21

daunorubicinol

trans-dihydrodiols

statil

akr7a2

dl-glyceraldehyde

3alpha-hydroxysteroid

diol-epoxide

Reaction

Synonyms

AKR1A1, aldehyde reductase, aldehyde reductase II, ALR1, D-glucuronate dehydrogenase, D-glucuronate reductase, D-glucuronic reductase, galacturonate oxidoreductase, hexonate dehydrogenase, L-glucuronate reductase, L-gulonate NAD-3-oxidoreductase, L-hexonate:NADP dehydrogenase, More, NADP-L-gulonate dehydrogenase, PcGOR, TPN l-hexonate dehydrogenase, TPN-L-gulonate dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.19 glucuronate reductase

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Results	in table
245	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
35	Cofactor
46	Disease/ Diagnostics
2	General Stability
67	Inhibitors
11	kcat/KM [mM/s]
53	KM Value [mM]
2	Localization
10	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
25	Organism
8	Pathway
13	pH Optimum
4	pH Range
6	pH Stability
9	Purification (Commentary)
2	Reaction
8	Reaction Type
25	Reference
27	Source Tissue
8	Specific Activity [micromol/min/mg]
2	Storage Stability
72	Substrates and Products (Substrate)
7	Subunits
24	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
4	Temperature Stability [°C]
14	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.19 - glucuronate reductase

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D-glucuronate + NADPH

L-gulonate + NADP+

6 entries

D-glucuronate + NADPH + H+

? + NADP+

Rattus norvegicus

ALR1

711916

D-glucuronolactone + NADPH

L-gulonolactone + NADP+

2 entries

gamma-hydroxybutyrate + NADP+

succinic semialdehyde + NADPH

Mesocricetus auratus

preverably in a coupled reaction in vivo with reduction of D-glucuronate

286147

L-gulonate + NADP+

D-glucuronate + NADPH

3 entries