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1.1.1.176: 12alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 12alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.176

Reaction

cholate
+
NADP+
=
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate
+
NADPH
+
H+

Synonyms

12alpha-HSDH, 12alpha-hydroxy steroid dehydrogenase, CDD59475, dehydrogenase, 12alpha-hydroxy steroid, Elen_2515, NAD+-dependent 12alpha-HSDH, NAD-dependent 12alpha-hydroxysteroid dehydrogenase, NADP+-dependent 12alpha-HSDH, NADP-12alpha-hydroxysteroid dehydrogenase, NADP-dependent 12alpha-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.176 12alpha-hydroxysteroid dehydrogenase

Sequence

Sequence on EC 1.1.1.176 - 12alpha-hydroxysteroid dehydrogenase

Please use the AA Sequence and Transmembrane Helices Search for a specific query.
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
12AH_CLOS4
Clostridium sp. (strain ATCC 29733 / VPI C48-50)
29
0
2900
Swiss-Prot
-
B6FYX7_CLOHT
Clostridium hiranonis (strain DSM 13275 / JCM 10541 / KCTC 15199 / TO-931)
266
0
28492
TrEMBL
-
C0BWQ2_9FIRM
259
0
27961
TrEMBL
-
R7AM69_9ACTN
266
0
28331
TrEMBL
other Location (Reliability: 2)