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1.1.1.17: mannitol-1-phosphate 5-dehydrogenase

This is an abbreviated version!
For detailed information about mannitol-1-phosphate 5-dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.17

Reaction

D-mannitol 1-phosphate
+
NAD+
=
D-fructose 6-phosphate
+
NADH
+
H+

Synonyms

BbMPD, BMMGA3_01075, BMMGA3_RS01080, D-mannitol-1-phosphate dehydrogenase, dehydrogenase, mannitol 1-phosphate, EsM1PDH1, EsM1PDH2, EsM1PDH3, fructose 6-phosphate reductase, HAD hydrolase, family IA, variant 3, hexose reductase, HMPREF0010_00722, long-chain mannitol-1-phosphate 5-dehydrogenase, long-chain mannitol-1-phosphate dehydrogenase, M1PDH, M1PDH1, M1PDH2, M1PDH3, mannitol 1-phosphate 5-dehydrogenase, mannitol 1-phosphate dehydrogenase, mannitol-1-phosphate dehydrogenase, More, MPD, MpdA, MPDH, MPDH1, MPDH2, MPDH3, Mtl-1-P dehydrogenase, MtlD, NAD+-dependent mannitol-1-phosphate dehydrogenase, NADH-dependent mannitol-1-phosphate 5-dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.17 mannitol-1-phosphate 5-dehydrogenase

Expression

Expression on EC 1.1.1.17 - mannitol-1-phosphate 5-dehydrogenase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
differential gene expression analysis of Bacillus methanolicus strain MGA3 cells grown on arabitol as compared to mannitol via transcriptome sequencing (RNA-seq), quantitative RT-PCR expression analysis, the enzyme can be induced by arabitol
expression of MtlD is strongly dependent on high osmolarity, not discriminating between different salts or sugars
in Bacillus methanolicus, RNA levels for atlD are higher while lower for mtlD during growth with both carbon sources as compared to growth with mannitol alone
in Corynebacterium glutamicum, arabitol induces expression of genes rbtT, mtlD, sixA, xylB and atlR, and glucose represses expression of mtlD
induction of the enzyme in cell culture by isopropyl 1-thio-beta-D-galactopyranoside
M1PDH becomes strongly upregulated during heat shock
-
the enzyme is salt-dependent and salt-induced, overview
-
the presence of glycine betaine or choline repress promoter activation