1.1.1.160: dihydrobunolol dehydrogenase

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For detailed information about dihydrobunolol dehydrogenase, go to the full flat file.

Reaction

Synonyms

bunolol reductase, dehydrogenase, dihydrobunolol

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.160 dihydrobunolol dehydrogenase

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1	CAS Registry Number
3	Cofactor
1	Localization
1	Natural Substrates/ Products (Substrates)
1	Organism
1	pH Optimum
1	Reaction
3	Reaction Type
1	Reference
1	Source Tissue
1	Storage Stability
2	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 1.1.1.160 - dihydrobunolol dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH

(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+

Homo sapiens

-

i.e. bunolol, r, also acts more slowly with NAD+

389408

i.e. dihydrobunolol

389408

r

(+,-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH

?

Homo sapiens

-

i.e. bunolol, metabolism of bunolol, a potent beta-adrenoceptor blocking agent in human liver

389408

-

-

?