1.1.1.159: 7alpha-hydroxysteroid dehydrogenase
This is an abbreviated version!
For detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.159
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1.1.1.159
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chenodeoxycholic
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cholic
-
testosteroni
-
bacteroides
-
thin-layer
-
3alpha-hydroxysteroid
-
synthesis
-
fragilis
-
7alpha-oh
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glycochenodeoxycholic
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nadp-dependent
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ursodeoxycholic
-
perfringens
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degradation
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analysis
- 1.1.1.159
-
chenodeoxycholic
-
cholic
- testosteroni
- bacteroides
-
thin-layer
-
3alpha-hydroxysteroid
- synthesis
- fragilis
-
7alpha-oh
-
glycochenodeoxycholic
-
nadp-dependent
-
ursodeoxycholic
- perfringens
- degradation
- analysis
Reaction
Synonyms
7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid, J-1-1, NADP(H)-dependent 7alpha-HSDH, NADP(H)-dependent 7alpha-hydroxysteroid dehydrogenase, NADP+-dependent 7alpha-HSDH, nicotinamide adenine dinucleotide phosphate-dependent 7alpha-hydroxysteroid dehydrogenase
ECTree
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KM Value
KM Value on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase
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0.32 - 0.34
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl glycine
-
-
0.0601
chenodeoxycholic acid
mutant enzyme Q255L/C260S, at pH 8.0 and 25°C
0.0661
chenodeoxycholic acid
wild type enzyme, at pH 8.0 and 25°C
0.34
NADP+
wild-type enzyme, pH and temperature not specified in the publication
0.69
NADP+
wild type enzyme, pH and temperature not specified in the publication
0.72
NADP+
mutant R194G, pH and temperature not specified in the publication
0.96
NADP+
mutant enzyme R16A/R194A, pH and temperature not specified in the publication
1.77
NADP+
mutant R16G, pH and temperature not specified in the publication
2.95
NADP+
mutant enzyme T15A/R16A/R194A, pH and temperature not specified in the publication
4.25
NADP+
mutant enzyme R16A, pH and temperature not specified in the publication
4.71
NADP+
mutant enzyme R194A, pH and temperature not specified in the publication
12.33
NADP+
mutant enzyme T15A, pH and temperature not specified in the publication