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1.1.1.1: alcohol dehydrogenase

This is an abbreviated version!
For detailed information about alcohol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.1

Reaction

a primary alcohol
+
NAD+
=
an aldehyde
+
NADH
+
H+

Synonyms

(R)-specific alcohol dehydrogenase, 40 kDa allergen, Aadh1, acetaldehyde-alcohol dehydrogenase, ADH, ADH 1, ADH class III, ADH I, ADH II, ADH-10, ADH-A, ADH-A2, ADH-B2, ADH-C2, ADH-HT, ADH-I, ADH1, ADH1B, ADH1C, ADH1C*1, ADH1C*2, Adh1p, ADH2, ADH3, ADH4, ADH5, ADH6Hp, ADH8, AdhA, AdhB, AdhC, AdhD, AdhE, ADHES77, ADS1, AFPDH, alcohol dehydrogenase, alcohol dehydrogenase (NAD), alcohol dehydrogenase 1, alcohol dehydrogenase 10, alcohol dehydrogenase 2, alcohol dehydrogenase 3, alcohol dehydrogenase 5, alcohol dehydrogenase class-P, alcohol dehydrogenase D, alcohol dehydrogenase GroES domain protein, alcohol dehydrogenase I, alcohol dehydrogenase II, Alcohol dehydrogenase-B2, alcohol dependent dehydrogenase, alcohol-aldehyde/ketone oxidoreductase, NAD+-dependent, alcohol:NAD+ oxidoreductase, aldehyde dehydrogenase, aldehyde reductase, aldehyde/alcohol dehydrogenase, ALDH, aliphatic alcohol dehydrogenase, alpha-ketoaldehyde dehydrogenase, anti-Prelog reductase, APE2239, APE_2239.1, ARAD1B16786p, bi-functional alcohol/aldehyde dehydrogenase, bifunctional acetaldehyde-alcohol dehydrogenase, bifunctional alcohol/aldehyde dehydrogenase, CHY1186, class I ADH, class I ALDH, class II ADH, class III ADH, class III alcohol dehydrogenase, class IV ADH, Cm-ADH2, Cthe_0423, DADH, dehydrogenase, alcohol, ethanol dehydrogenase, FALDH, FDH, Gastric alcohol dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, glutathione-dependent formaldehyde dehydrogenase/alcohol dehydrogenase, GSH-FDH, GSH-FDH/ADH, HLAD, hLADH, HpADH3, HtADH, HvADH1, HVO_2428, iron-containing alcohol dehydrogenase, KlADH4, KlDH3, KmADH3, KmADH4, LSADH, medium chain alcohol dehydrogenase, medium-chain NAD+-dependent ADH, medium-chain secondary alcohol dehydrogenase, MGD, More, NAD(H)-dependent alcohol dehydrogenase, NAD+-ADH, NAD+-dependent (S)-stereospecific alcohol dehydrogenase, NAD+-dependent alcohol dehydrogenase, NAD+-dependent SDR, NAD+-linked alcohol dehydrogenase 1, NAD+-linked methylglyoxal dehydrogenase, NAD-dependent alcohol dehydrogenase, NAD-dependent medium-chain ADH, NAD-specific aromatic alcohol dehydrogenase, NADH-alcohol dehydrogenase, NADH-aldehyde dehydrogenase, NADH-dependent alcohol dehydrogenase, NADH-dependent anti-Prelog specific ADH, NADH:p-NTF-reductase, Octanol dehydrogenase, Pcal_1311, PF0991 protein, PF1960, PFADH, primary alcohol dehydrogenase, Retinol dehydrogenase, SaADH, SaADH2, Saci_1232, SADH, SCAD, sec-ADH A, short-chain ADH, short-chain dehydrogenase/reductase, short-chain NAD(H)-dependent dehydrogenase/reductase, slr1192, SSADH, SsADH-10, SSO2536, ST0053, Ta1316 ADH, TaDH, TBADH, Teth39_0206, Teth39_0218, Teth514_0627, TK0845, Tsac_0416, Y-ADH, YADH, YADH-1, yeast alcohol dehydrogenase, YIM1, YLL056C, YMR152W, Ymr152wp

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.1 alcohol dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.1 - alcohol dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
105000
-
buffer containing 25 mM NaCl, gel filtration
109000
sucrose density gradient centrifugation
110000
-
gel filtration
116000
130000
-
ADH I, gel filtration
133000
gel filtration
138000
gel filtration
140000
145000
-
enzyme form ADH-I, glycerol density gradient centrifugation
150000
150300
-
electrospray mass spectrometry
152000
-
gel filtration
160000
164000
-
gel filtration
176000
Sporotrichum pulverulentum
-
non-denaturing PAGE
180000 - 440000
dimeric-tetrameric enzyme, native PAGE
24600
-
1 * 24600, SDS-PAGE
25000
-
gel filtration
26000
-
4 * 26000, SDS-PAGE
26961
-
4 * 26961, calculated from sequence
27000
gel filtration
27024
4 * 27024, ESI-MS analysis
27800
28000
28900
-
2 * 28900, SDS-PAGE
28978
29000
290000
-
gel filtration
30000
31000
31100
-
2 * 31100, enzyme form ADH-II, SDS-PAGE
31464
1 * 31000, SDS-PAGE, 1 * 31464, calculated
31997
-
x * 31997, amino acid sequence calculation
32000
1 * 32000, SDS-PAGE
320000
Megalodesulfovibrio gigas
-
gel filtration
34700
-
2 * 34700, enzyme form ADH-I, SDS-PAGE
35000
36000
36010
4 * 36010, Ta1316 ADH, calculated from amino acid sequence
36411
x * 36411, calculated, x * 37000, SDS-PAGE
36900
-
2 * 36900, SDS-PAGE
37000
37066
x * 37066, calculated
37200
calculated molecular weight
37311
x * 37311, calculated
37443
x * 37443, ADH1, calculated from sequence
37477
4 * 37477, calculeted from sequence
37500
-
x * 37500, SDS-PAGE
37585
-
4 * 37585, electrospray mass spectrometry
37588
-
4 * 37588, calculated from amino acid sequence
37591
-
4 * 37591, electrospray mass spectrometry
37600
4 * 37600, SDS-PAGE
37983
x * 37983, ADH3, calculated from sequence
38000
39000
39500
isozyme ADH3, apparent molecular weight deduced from electrophoretic mobility
39570
4 * 39570, calculated from sequence
39720
isozyme ADH3, calculated from amino acid sequence
39870
isozyme ADH1C, calculated from amino acid sequence
400000
-
gel filtration
40220
isozyme ADH2, calculated from amino acid sequence
40500
41000
41300
-
x * 41300, SDS-PAGE
41700
-
2 * 41700, enzyme form CM-I: a polypeptide chain + C polypeptide chain, enzyme form CM-II: B-chain + C-chain, enzyme form CM III, homodimer of C chains, SDS-PAGE
42000
43000
45000
46000
-
2 * 46000, SDS-PAGE
47000
-
2 * 47000, isoenzyme C2, SDS-PAGE
48600
-
2 * 48600, alcohol dehydrogenase domain, SDS-PAGE. Unlike the native ADHE, the alcohol dehydrogenase domain alone does not assemble into spirosome structures
54600
-
gel filtration
55600
-
gel filtration
56000
-
gel filtration
56700
deduced from amino acid sequence
57600
-
gel filtration
58000
59900
-
gel filtration
60000 - 80000
-
gel filtration
66000
-
recombinant enzyme expressed from Hansenula polymorpha, gel filtration
67000
-
enzyme form ADH-II, glycerol density gradient centrifugation
68000
-
gel filtration
70000
70000 - 80000
-
gel filtration
72000
74000
74500
-
gel filtration
76000
gel filtration
76000 - 77000
-
equilibrium sedimentation
77330
-
equilibrium sedimentation
78000
-
ultracentrifugation under non-denaturing conditions
78000 - 85000
-
amino acid analysis, ultracentrifugation
79000
-
isoenzyme B2, gel filtration
79000 - 84000
-
ultracentrifugal analysis
80000
81500
-
gel filtration
82700
-
equilibrium sedimentation
82750
-
enzyme form ADH-3, equilibrium sedimentation
83000
-
isoenzyme A2, gel filtration
85000
86000
88000
89000 - 91000
-
gel filtration
91480
calculated from sequence
94000
-
gel filtration
95000
-
enzyme form ADHII, gel filtration
96000
99000
-
alcohol dehydrogenase domain, dynamic light-scattering